Upon Tiber Island, since 293 BC, the Temple of Aesculapius, the god of healing. Inevitably many sick were cared for on the island and the tradition still continues until this day, a hospital still being there today.
Model of Rome in the days of Constantine the Great
Museo della Civilta, Rome
Take a close look at the model and you can see that Tiber Island used to have large structures built at either end of it, looking like the stern and bow of a ship.